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NONCODE 16 has also introduced three important new features:.
Noncode 2016 an informative and valuable data source of long non coding rnas. The source of NONCODE 16 includes the previous ver-. In this work, we link the origins and functions of some lncRNAs to retroposition, a process resulting in the creation of intronless copies (retrocopies) of the so-called parental genes. Non-coding RNAs (ncRNAs) are a type of RNA molecule, which are not translated into proteins.
Similar to the former iterations of NONCODE , the source of NONCODE 16 includes the previous versions of NONCODE, the collated literature and other public databases. Now, there are 17 species in NONCODE (human, mouse, cow, rat, chicken, fruitfly, zebrafish, celegans, yeast). CAS Article Google Scholar.
Since NONCODE 16 was released two years ago, the amount of novel identified ncRNAs has been enlarged by the reduced cost of next-generation sequencing, which has produced an explosion of newly identified data. View Paper (PubMed) View Publication. Zhao Y, Li H, Fang S, Kang Y, Wu W, Hao Y, Li Z, Bu D, Sun N, Zhang MQ, et al:.
Compared to protein-coding genes, they are often expressed at low levels and are restricted to a narrow range of cell types or developmental stages. A Language and Environment for Statistical Computing. CAS PubMed Article PubMed Central Google Scholar.
12 Zhao Y , Li H , Fang S , Kang Y , Wu W , Hao Y , Li Z , Bu D , Sun N , Zhang MQ , Chen R (16) NONCODE 16:. Bu D, Yu K, Sun S, Xie C, Skogerbo G, Miao R. An informative and valuable data source of long non-coding RNAs, Nucl Acids Res 44:D3–8, 16.
An informative and valuable data source of long non-coding RNAs. An informative and valuable data source of long non-coding RNAs. We searched PubMed using the key words ‘ncrna’, ‘noncoding’, ‘non-coding’, ‘no code’, ‘non-code’, ‘lncrna’ and ‘lincrna’, and found 6532 new articles since 1 June 13 (the last collection date for NONCODE).
NONCODE (current version v5.0) is an integrated knowledge database dedicated to non-coding RNAs (excluding tRNAs and rRNAs). An informative and valuable data source of long non-coding RNAs NONCODE 16:. An informative and valuable data source of long non-coding RNAs.
44 , D3 - D8. Crossref, Medline, Google Scholar;. The NONCODE human lncRNA database annotated 527,336.
The development of high‐throughput sequencing technologies offers the opportunities to explore a wealth of novel, unannotated transcripts, especially long non‐coding transcripts. Zhao Y, Li H, Fang S, Kang Y, Wu W, Hao Y, Li Z, Bu D, Sun N, Zhang MQ et al (16) NONCODE 16:. 10.1093/nar/gkv1252 OpenUrl CrossRef PubMed.
The recently reduced cost of RNA sequencing has produced an explosion of newly identified data. RNA editing sites in lncRNA transcripts. Zhao Y, Li H, Fang S, Kang Y, Wu W, Hao Y, Li Z, Bu D, Sun N, Zhang MQ, Chen R, NONCODE 16:.
An informative and valuable data source of long non-coding RNAs. These lncRNAs are defined as RNA. Crossref, Medline, Google Scholar;.
Zhao Y, Li H, Fang S, Kang Y, Wu W, Hao Y, et al. View Article PubMed/NCBI Google Scholar 24. An informative and valuable data source of long non-coding RNAs.
Crossref Medline Google Scholar;. And (iii) an interface to choose high-quality datasets through predicted scores, literature support and long-read sequencing method support. An informative and valuable data source of long non-coding RNAs.
A class of RNA molecules that is identified now as long‐noncoding‐RNAs (lncRNAs). Indexing microRNA targets on non-coding transcripts DIANA-LncBase v2:. Necsulea A, Soumillon M, Warnefors M, et al.
Indexing microRNA targets on non-coding transcripts. Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) Journal Home;. Nucleic Acids Res 44(D1):D3–D8 CrossRef PubMed Google Scholar.
Fang et al., “NONCODE 16:. Antisense transcription in the mammalian transcriptome. BMC genomics 16 , 680, https://doi.
In this review, we discuss the challenges related to long non‐coding RNA expression profiling, highlight how cancer long non‐coding RNAs provide new opportunities for cancer diagnosis and. An informative and valuable data source of long non-coding RNAs. Nucleic Acids Research, 15, 44 (D1):D3-D8.
Xie C, Yuan J, Li H, et al. Zhao Y, Li H, Fang S, Kang Y, wu W, Hao Y, et al. 10.1093/nar/gkv1252 PubMed Abstract | CrossRef Full Text | Google Scholar.
An informative and valuable data source of long non-coding RNAs. Zhao Y, Li H, Fang S, et al. We searched PubMed using the key words ‘ncrna’, ‘noncoding’, ‘non-coding’, ‘no code’, ‘non-code’, ‘lncrna’ and ‘lincrna’, and found 6532 new articles since 1 June 13 (the last collection date for NONCODE).
As a consequence, the diversity of their isoforms is still far from being recorded and catalogued in its. Fang, Shuangsang Nucleic Acids Research, Vol. Nucleic Acids Res 16;44:D3-8.
10.1093/nar/gkv1252 PubMed Abstract | CrossRef Full Text | Google Scholar. An informative and valuable data source of long non-coding RNAs. Nucleic acids research 44 (D1), D3-D8 , 16.
Human Homo sapiens :. An informative and valuable data source of long non-coding RNAs Y Zhao, H Li, S Fang, Y Kang, W Wu, Y Hao, Z Li, D Bu, N Sun, MQ Zhang,. Zhao Y., Li H., Fang S.
3, 8, 9 These experiments have shown that in all cases, a class of very abundant, but not originally predicted, RNA molecules is present in the transcriptomes:. D3-D8 View in Article. Close Drawer Menu Open Drawer Menu Home.
An informative and valuable data source of long non-coding RNAs. An informative and valuable data source of long non-coding RNAs Y Zhao, H Li, S Fang, Y Kang, W Wu, Y Hao, Z Li, D Bu, N Sun, MQ Zhang,. Crossref, Medline, Google Scholar.
Nucleic Acids Research, 14, 42 (Databaseissue):98-103. An informative and valuable data source of long non-coding RNAs. The estimated number of human lncRNA genes ranges from ~16,000 predicted by GENCODE 6 to ~100,000 predicted by NONCODE 7.
Nat Rev Genet 17, 601–614. Long non-coding RNAs (lncRNAs) are a class of intensely studied, yet enigmatic molecules that make up a substantial portion of the human transcriptome. Ma L, Bajic VB, Zhang Z.
167,150 101,700 mouse Mus musculus :. Ulitsky I (16) Evolution to the rescue:. Zhao Y, Li H, Fang S, Kang Y, Wu W, Hao Y, et al.
Similar to the former iterations of NONCODE (18–21), the source of NONCODE 16 includes the previous versions of NONCODE, the collated literature and other public databases. Long non-coding RNAs (lncRNAs) form a substantial component of the transcriptome and are involved in a wide variety of regulatory mechanisms. Xie C, Yuan J, Li H, Li M, Zhao G, Bu D.
An informative and valuable data source of long non-coding RNAs. An informative and valuable data source of long non-coding RNAs, Nucleic Acids Res 44(D1) :D3, 16. 130,558 86,935 cow Bos taurus.
, 44 , D3–D8. There are excellent recent articles documenting these findings. View Article PubMed/NCBI Google Scholar 19.
Exploring the world of long non-coding RNA genes. Zhao Y,Li H,Fang S,Kang Y,Wu W,Hao Y,Li Z,Bu D,Sun N,Zhang MQ,Chen R Nucleic Acids Res 15. Especially long non-coding RNAs (lncRNAs).
An informative and valuable data source of long non-coding RNAs. An informative and valuable data source of long non-coding RNAs. Zhao Y, Li H, Fang S, Kang Y, Wu W, Hao Y, Li Z, Bu D, Sun N, Zhang MQ, Chen R.
PMC free article PubMed Google Scholar. An informative and valuable data source of long non-coding RNAs J. Number of lncRNA transcripts.
An informative and valuable data source of long non-coding RNAs. An informative and valuable data source of long non-coding RNAs. An informative and valuable data source of long non-coding RNAs.
(ii) the relationships between lncRNAs and diseases;. Non-coding RNAs (ncRNAs) are a key regulator of gene expression, which can be divided into classes based on their mechanisms of action and genomic origin, including housekeeping ncRNAs and regulatory ncRNAs 1,5.The housekeeping ncRNAs comprise of ribosomal RNAs (rRNAs), transfer RNAs and small nucleolar RNAs (snoRNAs). Yi Z, Hui L, Fang S, et al.
A web server for functional annotation of long non-coding RNAs, Nucl Acids Res 39:W118–W124, 11. Although higher organisms transcribe lots of RNAs, the proteins or polypeptides encoded through this transcript only occupy 2% of the entire genomes. An informative and valuable data source of long non-coding RNAs.
The annotation of more than 300 000 human lncRNAs (hg19) was obtained from LNCat (), the most comprehensive annotation resources for human lncRNAs.The lncRNA annotation of mouse (mm10) was downloaded from NONCODE (version 16) and GENCODE (M10) (), while the lncRNA annotations of rhesus (mac3) and fly (dm6) were downloaded from NONCODE (version 16). The remaining are noncoding RNAs (ncRNAs). 36, 37 Compared with protein‐coding genes, lncRNAs are found to constitute a much larger proportion, 38 which may serve as a rich source of potential biomarkers.
Using comparative genomics to understand long non-coding RNAs. An informative and valuable data source of long non-coding RNAs. A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression.
Zhao Y, Li H, Fang S, Kang Y, Wu W, Hao Y, et al. Article PubMed Google Scholar. An informative and valuable data source of long non-coding RNAs journal, November 15 Zhao, Yi;.
Exploring the world of long non-coding RNA genes. Number of lncRNA genes.;. Y Zhao et al., NONCODE 16:.
MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of. Genome-wide characterization of long intergenic non-coding RNAs (lincRNAs) provides new insight into viral diseases in honey bees Apis cerana and Apis mellifera. Additionally, a significant proportion of our noncoding DNA is transcribed into long noncoding RNAs (lncRNAs), a largely unexplored class of noncoding RNAs >0 nucleotides long 5.
In humans, less than 2% of the genome correlates to the coding region, despite a transcription rate as high as even 93% 3,4,5.More recently, the exponential increase in next-generation sequencing and other similar high-throughput methods has made available a plethora of information on ncRNAs. An informative and valuable data source of long non-coding RNAs. “Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and.
On the classification of long non-coding RNAs. Q Liao et al., ncFANs:. Nucleic acids research 44 (D1), D3-D8 , 16.
Long noncoding RNAs (lncRNA), a class of nonprotein-coding RNA molecules, regulate gene imprinting and embryonic development.
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